Human Chromosomes (Lesson)

  • Uploaded By: Quincy McDuffie
  • For Citation:Christopher J. Halweg, Whitney M. Jones, Elizabeth A. Ruedi, Marion E. Gardner, Hannah Clark, and Claire L. Gordy
  • Description:This is an in-class activity that demonstrates 3D printed models of human chromosomes, to assist students in learning about karyotypes.
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Lesson Overview

This lesson pairs models of human chromosomes with a guided-inquiry activity about karyotypes. This was designed to simulate the process of sorting chromosomes in actual genetic testing. The objective is to perform a karyotype by identifying every chromosome. Students will be given a full set (2 prints of full file) and a description of the each chromosome. Using the descriptions, students will pair the chromosomes with the homologs. Students can also identify chromosomal sex of the individual and translations, deletions or transmutations.

This lesson was created for the NCSU Genetics department through a Diversity Mini-Grant from North Carolina State University.

Learning Outcomes

At the end of this activity, students should be able to:

  1. Perform a karyotype by identifying every chromosome.
  2. Describe each chromosome.
  3. Using the descriptions, pair the chromosomes with the homologs.
  4. Identify the chromosomal sex of the individual, translations, deletions, and transmutations.

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Models used in this Lesson Plan